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Specs are compiled from manufacturer listings and verified buyer reviews and can change over time — please confirm the key details on the product page before buying.
If you want the short answer: buy a DGL supplement that lists a real deglycyrrhizinized licorice dose on the label, comes in the format you will actually take every day, and skips the sweeteners that can upset a sensitive gut. That is the whole decision. Everything else on a supplement label is packaging.
I’m Mohammad Maruf — the founder and writer behind Gardening Beyond. This guide is built by comparing the manufacturers’ published specifications and the patterns across verified customer reviews, so you get each pick’s real strengths and trade-offs instead of marketing spin.
Below you will find nine DGL options sorted from the crowd favorite down to the budget-friendly picks, each with the exact capsule count and formula detail you need to choose. Whether you chew tablets or swallow capsules, use this list of the best dgl supplement to match the format to your daily routine.
Our Picks at a Glance
How To Choose The Best DGL Supplement
The first thing to understand is what the letters mean. DGL stands for deglycyrrhizinized licorice — licorice root that has had glycyrrhizin removed. Glycyrrhizin is the compound in ordinary licorice that can push blood pressure up, so removing it is the entire point of buying DGL instead of plain licorice root.
Chewable or capsule
Chewables put the herb in direct contact with your mouth and throat on the way down, and most labels tell you to chew them before a meal. Capsules are easier to swallow and easier to carry, but they have to dissolve first. If you have braces or dentures, that chewing instruction is worth thinking about before you buy.
Read the extract ratio, not just the milligrams
A “10:1” or “20:1” extract means the powder was concentrated, so a 500 mg serving of a 20:1 extract started as far more raw herb. Two bottles can both say “500 mg” and deliver very different amounts of actual licorice. Check the ratio and the milligrams together.
Count your servings before you commit
A 200-capsule bottle sounds generous until you realise the label says two capsules per serving — that is 100 servings, not 200. Always divide the capsule count by the serving size to get real doses per bottle.
Check the sweetener list
Chewables usually need something to make licorice palatable. Common additions include fructose, mannitol, and sorbitol — sugar alcohols that some people with sensitive digestion notice. If you have reacted to sugar alcohols before, a capsule with no sweeteners at all is the simpler route.
Quick Comparison
| Model | Best For | Format | Units Per Bottle | Licorice Per Serving | Amazon |
|---|---|---|---|---|---|
| Integrative Therapeutics Rhizinate Fructose Free★ Best Overall | People who want a sugar-free chewable | Chewable tablet | 100 Count | — | Amazon |
| Integrative Therapeutics RhizinateBest Chewable Formula | Fans of the chocolate-style chewable | Chewable tablet | 100 Count | — | Amazon |
| Nature’s Way DGL Ultra Extra StrengthMost Popular Pick | Anyone replacing a prescription antacid habit | Chewable tablet | 90 Count | 75 mg GutGard extract | Amazon |
| Zazzee USDA Organic DGL Licorice 20:1 | Buyers who want organic certification | Vegan capsule | 120 Capsules | 20:1 extract | Amazon |
| 365 by Whole Foods Market DGL Plus | Chewable fans who want the biggest listed dose | Chewable tablet | 100 Tablets | 760 mg DGL | Amazon |
| HERBALICIOUS DGL Licorice Root Capsules | Capsule takers who want an organic label | Capsule | 100 Count | — | Amazon |
| Carlyle DGL | Stocking a long supply at a budget-friendly tier | Vegetarian capsule | 200 Capsules | — | Amazon |
| NaturesPlus Herbal Actives Licorice DGL | Standardized 500 mg doses in capsule form | Capsule | 60 Capsules | 500 mg | Amazon |
| Nutricost DGL Extract | Swallowers who want the strongest listed extract | Capsule | 120 Capsules | 500 mg 10:1 extract | Amazon |
In‑Depth Reviews
1. Integrative Therapeutics Rhizinate Fructose Free, DGL Supplement, 100 Count
Our pick — over 4.5★ from 650+ verified ratings; the strongest balance of quality and price.
The chewable that skips the sugar without skipping the taste test.
This is the pick for anyone who wants a chewable DGL but cannot handle the sweetener list on most of them. The label is explicit: no sugar, wheat, gluten, soy, dairy, artificial colors, and no preservatives, with less than 1% glycyrrhizin remaining. That last number is the one that matters most, because glycyrrhizin is the compound in ordinary licorice that can affect blood pressure. For a chewable, this is about as clean a formula sheet as you will find.
The bottle holds 100 chewable tablets, and it weighs 2.4 ounces — light enough that a spare pack disappears into a purse or a desk drawer without you noticing. And it is genuinely sugar-free, which separates it from the sweetened chewables in this list. If sugar alcohols or added sugars have bothered your stomach before, this is the chewable that sidesteps them entirely.
What earns it the top spot
- Chewable format with the guidance to chew before meals, so the herb meets your mouth and throat on the way down
- Contains less than 1% glycyrrhizin — the lowest glycyrrhizin figure stated anywhere in this list
- Free from wheat, gluten, soy, dairy, artificial colors, and preservatives, and it is fructose-free
- 100 tablets per bottle in a 2.4-ounce container that travels easily
- The most-praised thing among buyers is the lack of side effects, with effectiveness running right behind it
Where it asks for patience
- Still contains fructose, mannitol, and sorbitol — check the panel if sugar alcohols irritate your gut
- Taste divides people cleanly; the licorice flavour is brief but not universally liked
Reach for this if: you want a sugar-free chewable with the lowest stated glycyrrhizin level and the cleanest ingredient list here.
Look elsewhere if: sugar alcohols are a known trigger for you, or you would rather swallow a capsule than chew a tablet.
2. Integrative Therapeutics Rhizinate Digestive Support Supplement, 100 Count
The chocolate-ish chewable people describe as tasting like German chocolate.
Same brand, same 100-count chewable format, different formula — and this is the one for a buyer who wants a tablet that goes down pleasantly rather than a flavour you endure. It also carries less than 1% glycyrrhizin, keeps the wheat, gluten, soy, dairy, artificial colour, and preservative list clear, and asks you to use it as needed rather than on a fixed clock. For someone who only reaches for DGL on the days a meal sits badly, that flexibility is the whole appeal.
The tablet weighs in at 4.66 ounces for the bottle, which is chunky enough to sit stably on a countertop rather than tip over mid-morning. The feedback pattern is straightforward: it does the job reliably, owners describe fast results when discomfort hits after eating, and it holds up as a repeat purchase. The recurring scene in the reviews is someone who took it consistently, then found they needed it less and less, which is exactly the kind of routine you want from a chewable.
Two things to know before you commit. This version contains sugar, which matters if you are watching sugar intake or simply chose the fructose-free version above for that reason. And the label instructions changed at some point from chewing two tablets twenty minutes before meals to chewing three tablets after food morning and evening — if you are following a printed routine from an older bottle, check the current panel.
The formula trade: compared with the fructose-free Rhizinate at position one, this version adds sugar to the tablet. Both list less than 1% glycyrrhizin and both come as 100 chewable tablets, so the real fork in the road is the sweetener, not the licorice.
How it fits a day: the dosing lets you take it when you need it rather than on a rigid schedule, which suits people who want DGL as a backup rather than a daily obligation.
Picture this fit: you want a chewable that tastes good enough to take without bracing yourself, and you are not avoiding sugar.
The one caveat: sugar is in the formula, so if that is a deal you have already ruled out, the fructose-free version above is the smarter match.
3. Nature’s Way DGL Ultra Extra Strength, 75mg per Serving, Chocolate Flavored, 90 Count
The one people reach for when they are trying to step away from a daily antacid.
Here is what makes this bottle different from everything else on the page: it is built around GutGard deglycyrrhizinized licorice extract at 75 mg per serving, and the label speaks in extract terms rather than raw powder. It is a chocolate-flavoured chewable, 90 tablets to a bottle, and it weighs 8.8 ounces — the heaviest container in this group, which tells you the tablets are substantial in the hand. The chewable form also means the tablet is in contact with your mouth and throat as you chew, which is why the label asks for that rather than a swallow.
The reason this one earns its position is the dosing pattern. The directions are one tablet after food in the morning and one after food in the evening — a routine that slots into breakfast and dinner rather than demanding a twenty-minute pre-meal countdown. For anyone who has been relying on an over-the-counter antacid multiple times a day, that twice-daily anchor is the practical draw.
The trade-off is real and it comes up often: the formula appears to have changed, and a chunk of the feedback mentions the tablets arriving smaller, more bitter, and less chocolate-forward than they used to be. Owners who used it for years describe being disappointed by the new taste even while saying it still works. If you are buying for the flavour specifically, expect a bitter licorice edge rather than a dessert.
Why it keeps a spot
- GutGard deglycyrrhizinized licorice extract at 75 mg per serving — a named, standardized extract rather than a generic powder
- Only two tablets a day, both after food, so it fits naturally around breakfast and dinner
- 90 servings in the bottle, and it is gluten-free, vegan, and dairy-free with no salt, soy, or artificial colours or flavours
- The bottle itself is made with 97% post-consumer recycled materials
- Owners describe it working within minutes during a bad flare and keep it in a bag for that reason
What changed and what to expect
- The tablets are reported as smaller and more bitter than earlier versions of the same product
- Contains milk, so it is not a fit if you are avoiding dairy
The straightforward verdict: if you want a widely used chewable with a clear extract name on the label and a two-a-day rhythm, this is a strong default.
Think twice if: you are dairy-free or you specifically want the old chocolate taste people remember.
4. Zazzee USDA Organic DGL Licorice 20:1 Extract, 120 Vegan Capsules
The capsule for buyers who want the organic certificate in writing.
Two numbers define this bottle: the extract is concentrated at a 20:1 ratio, and the whole product carries USDA Certified Organic status. The 20:1 figure is the concentration multiplier — it means the extract was condensed from a much larger quantity of raw licorice, so a single capsule delivers a far denser dose than plain licorice powder would. The Certified Organic stamp is the harder one to find in this category, and it is the reason this pick holds a high-end spot instead of a mid-range one.
The bottle holds 120 vegan capsules and the label describes that as a four month supply. That math works out only if you take one capsule per day, which is worth checking against your own routine before you assume the bottle will last a season. Everything in it, including the capsule shell itself, is vegan, and the formula leaves out sweeteners, artificial flavours, wheat, corn, gluten, soy, milk, egg, fish, shellfish, and tree nut ingredients.
Owners consistently describe a capsule that goes down easily and a mild, pleasant licorice taste. The praise that comes up most is the overall quality, with digestive support running a close second. The trade-off is format speed: capsules have to dissolve before they release, and the feedback from the wider capsule-versus-chewable debate is that chewables tend to act faster because they are already broken down when they hit your throat. If you are choosing a capsule for convenience, this is a fair place to land, but go in knowing the format difference.
Certification, priced accordingly: this is the top of the value ladder here, and much of that is the USDA Organic certification. Nothing else in this list states a Certified Organic claim, so you are paying for a verified standard rather than a bigger pill.
A capsule-specific caveat: the label lists rice hull and rice powder as fillers. That is normal for capsules and harmless for most people, but if you are strict about filler-free formulas, it belongs on your radar.
Who it suits: you want organic certification and a vegan capsule you can take once a day.
Who should keep scrolling: you are chasing the fastest possible onset and can tolerate a chewable instead.
5. 365 by Whole Foods Market, DGL Plus Chewable Tablets, 100 Tablets
One chewable a day, and a DGL number that stands out on the shelf.
If you are the type of buyer who compares numbers before buying, this is your bottle. Owners who use it point to the DGL content as the reason they switched, and describe reaching the same daily routine with a single chewable that would have taken more tablets elsewhere. It is a 100-tablet bottle of chewable DGL Plus, free from artificial colours, flavours, and preservatives, and manufactured following GMP guidelines — the good manufacturing practice standard that governs how supplement plants operate. The bottle weighs 1.6 ounces, the lightest container in this set and an easy one to tuck into a travel bag.
The label also lists L-glycine alongside the DGL, which is why the product is called DGL Plus rather than plain DGL. That combination is the reason some owners mention it beats the plain licorice root extract they used previously. The honest catch is the texture: the tablets are firm, and chewing them is a chore if your teeth are compromised. Braces, crowns, or dentures make this a genuine consideration, and one buyer in the feedback said exactly that.
Taste divides people the same way it does across the whole category — strong licorice and anise, with some loving it and some finding it harsh. The effects are the more interesting story: plenty of buyers describe it helping their stomach, and a few describe the opposite. That is a fit question rather than a quality question, which is why a single bottle is the sensible test before committing to a multi-month supply.
Why it sits this high: it pairs one of the strongest stated DGL doses in this list with glycine, which is a combination you cannot get in a plain licorice capsule.
One buyer pattern to respect: the feedback splits between people it helps and people it does not. If you have a delicate stomach, one bottle is a reasonable test before you stock up.
Worth it if: you want the biggest stated DGL number in a once-a-day chewable and you can chew firm tablets comfortably.
Not the right pick if: you wear braces or removable dental work, where a capsule is simply easier.
6. HERBALICIOUS DGL Licorice Root Capsules, 100 Count, Organic and Non-GMO
Licorice-forward capsules that people describe as easy to swallow and pleasant to taste.
This bottle of 100 capsules is built on organic licorice root extract with the glycyrrhizin removed, and the clean-label line-up is the selling point: non-GMO, gluten-free, and free from artificial additives, fillers, soy, and dairy. The package weighs 2.36 ounces, so it is a slim bottle that takes up almost no room in a cabinet or a carry-on. If you travel and want something that does not spill powder or crumble, the capsule format is the practical choice here.
The feedback on this one leans on taste and ease more than anything else. Owners describe a delicious licorice flavour and a capsule that goes down without fuss, and the brand earns repeat orders from that. It also plays well as a carry-along — the kind of thing people keep in a bag so it is there when a meal starts sitting wrong.
The caveats are worth stating plainly. At least one reviewer noted no noticeable difference at all, which is the honest reality of any supplement. If you take blood pressure medication or have a heart condition, that is a conversation to have with a qualified healthcare professional before you order, not after.
Where it shines: the organic, non-GMO, filler-free panel and a licorice taste that people actually enjoy rather than tolerate.
The thing to take seriously: the label is a capsule, not a candy. The glycyrrhizin may be removed, but the general cautions around licorice still apply, and buyers confirm it themselves in the feedback.
Pick this one if: you want an organic capsule with a genuinely pleasant licorice flavour and a bottle slim enough to travel with.
Pass if: you take blood pressure medication or have a heart condition — clear that with your healthcare professional first.
7. Carlyle DGL, 200 Capsules, Deglycyrrhizinated Licorice
Two hundred capsules in one bottle, and the biggest count on this entire list.
If volume per bottle is what you are shopping on, this is the runaway answer. Carlyle packs 200 capsules where the closest competitor in this group offers 60 — that is more than three times the capsule count of the NaturesPlus bottle above. Both are budget-friendly tiers, but only one of them lets you go months between reorders. The capsules are vegetarian, and the formula is free from gluten, wheat, yeast, lactose, soy, artificial flavour, and preservatives, plus non-GMO. The bottle weighs 3.53 ounces.
The texture and the taste are designed out of the equation here — no chewing, no licorice flavour, no anise aftertaste. That suits a buyer who wants DGL as a background habit rather than a ritual. Owners describe taking them regularly and carrying them in a purse or bag, easy to swallow, and useful as part of a wider gut-health routine rather than a one-off.
The honest note is that this is a supplement people report using as one piece of a regimen — alongside digestive enzymes, teas, and other herbs — rather than a single silver bullet. The lab-tested, trusted-ingredients claim on the label is Carlyle’s own quality statement, and it is worth reading every supplement label critically regardless of brand. If you want the cheapest cost per capsule with the fewest reorders, this bottle is the practical answer.
Why it wins on volume
- 200 capsules per bottle — more than the 60 in the NaturesPlus bottle and the highest count in this list
- Vegetarian capsules that swallow easily with no licorice taste to manage
- Free from gluten, wheat, yeast, lactose, soy, artificial flavour, and preservatives, and non-GMO
- Owners treat it as a staple they restock, not a one-time experiment
What to weigh
- The label states “Licorice” on the front; check the serving size on the panel to see how long the 200 capsules really last you
- It is positioned as part of a broader routine, so expect to pair it with other habits rather than rely on it alone
Best for: the shopper who wants the most capsules per bottle and no licorice taste at all.
Better elsewhere if: you want a chewable, or you want the exact milligram dose printed on the front of the label.
8. NaturesPlus Herbal Actives Licorice (DGL) Capsules, 60 Capsules, Non-GMO and Vegan
A clean 500 mg number and a capsule that people mostly reach for on a strict schedule.
This is the bottle for someone who likes the label to state one clear figure. Each capsule delivers 500 mg of deglycyrrhizinized licorice in a standardized formula — standardized meaning every capsule is meant to contain the same amount rather than varying batch to batch. It is non-GMO, vegan, and gluten-free, produced in facilities the maker states are FDA and NSF registered and maintained under cGMP compliance. The bottle holds 60 capsules and measures 1.9 x 1.9 x 3.7 inches, making it the most compact bottle in this comparison.
The feedback on this one is unusually decisive on the core question: reviewers describe it working better than the antacid they came from, settling upset stomachs, and getting them through a day without the burn. Those are strong words, and they come up repeatedly enough to be the pattern rather than an outlier. The one-capsule-daily direction also keeps the routine simple.
Now the honest parts. Taste is the most-divided topic — a bitter licorice edge that some find fine and some do not. Several reviewers describe a more involved dosing approach with capsules before meals and at bedtime, which means your actual bottle may empty faster than the label’s once-a-day suggestion implies. And one account describes a serious reaction in a person already on blood pressure medication, with symptoms returning on a second attempt. If hypertension or blood pressure medication is part of your picture, that is a conversation for your doctor before this goes in your cart.
The 500 mg case: a standardized dose is easier to reason about than a powder with no stated milligram figure, and 500 mg per capsule is stated right on the label.
The thing nobody mentions until they buy: many owners dose two capsules before meals plus two at bedtime rather than one a day — so plan your bottle count around real-world use, not the minimum.
Suits you if: you want a standardized 500 mg capsule from a long-established brand, and you will follow a pre-meal schedule.
Not for you if: you have hypertension or take blood pressure medication — speak to a healthcare professional first.
9. Nutricost DGL Extract, 120 Capsules, 120 Servings, Gluten-Free
One serving per capsule, 120 servings per bottle, and a 10:1 extract behind it.
Read the ratio first, because it is the whole argument for this bottle. Nutricost uses a 10:1 extract at 500 mg per serving, meaning the powder was concentrated tenfold from the raw herb before it was put in the capsule. It is a one-capsule-per-serving formula with 120 capsules in the bottle, so 120 servings — the heaviest bottle here at 3.84 ounces and the biggest physical footprint at 2.5 x 2.5 x 4.5 inches. Compared side by side with the Rhizinate Fructose Free bottle, which weighs 2.4 ounces, this one is 60% more by weight, and the bottle is 32% larger than the compact NaturesPlus container. Bigger bottle, more capsules, heavier to ship.
Manufacturing is where this pick makes its case: an NSF Certified GMP Compliant facility, with each batch going through third-party testing at independent ISO-accredited laboratories to verify potency and purity. That is a specific, checkable production standard rather than a vague quality promise, and it is why this sits above the plain capsules in this list.
The catch is the format. Several buyers describe capsules working less well than chewables, with one noting that a chewable dissolves and gets to work faster, and another frustrated that they ordered capsules by mistake. If you have already decided DGL works for you as a capsule, the extract strength and testing standard make this a solid buy. If you have never tried DGL before, understand that the capsule experience is different from the chewable one before you commit to a 120-serving bottle.
What makes it stand out
- 500 mg of 10:1 DGL deglycyrrhizinized licorice extract per serving — a concentrated rather than raw powder
- 120 capsules equals 120 servings, so the bottle lasts as long as the count suggests
- Made in an NSF Certified GMP Compliant facility with each batch third-party tested by independent ISO-accredited labs
- Gluten-free and built for a three-times-daily-between-meals routine
Where it comes up short
- Capsule form means slower onset than a chewable — a repeated point in the feedback
- Taste feedback splits, with several describing it closer to smoked wood than licorice
- It is the heaviest and largest bottle in this comparison at 3.84 ounces
Made for: a capsule-first buyer who wants a stated 10:1 extract and documented third-party batch testing.
Questionable if: you have never used DGL before — chewables are the faster route and the better first experiment.
Understanding the Specs
Deglycyrrhizinized (DGL) versus plain licorice root
Regular licorice root contains glycyrrhizin (a compound that can raise blood pressure), and that compound is why licorice carries warnings around blood pressure. DGL is licorice root with that compound stripped out, which is the version you will find in the bottles on this page — some labels state the remaining glycyrrhizin level, and one here lists less than 1%. Often the difference between a supplement you use daily and one you use carefully depends on that single number on the panel.
Extract ratio and milligrams per serving
An extract ratio such as 10:1 or 20:1 tells you how concentrated the powder is — a 20:1 extract started as twenty times its final weight in raw herb. Milligrams per serving tells you how much of that concentrated powder you get in one dose. A higher ratio with a lower milligram figure can still deliver more raw herb than a lower ratio with a higher figure, which is why serious buyers read both numbers together rather than one alone.
Chewable tablets versus capsules
Chewables are typically chewed so the tablet breaks down in your mouth before it reaches your throat, and many labels time that chew to about twenty minutes before a meal. Capsules swallow whole and dissolve further down the digestive tract, which the feedback describes as a slower start but a more comfortable daily habit for some people. Neither format is better — the right one is the format you will actually take twice a day, every day.
Servings per bottle and the real cost of a dose
A capsule count is not a serving count. If the label says two capsules per serving, a 100-capsule bottle is 50 servings, not 100. Divide the count by the serving size before you decide whether a bottle lasts a season or a month.
FAQ
What does DGL mean and how is it different from plain licorice root?
Are DGL chewables or capsules better?
Can I take a DGL supplement alongside a prescription antacid?
How long does a bottle of DGL capsules actually last?
Does DGL contain sugar or sweeteners?
What does the extract ratio on a DGL label mean?
Should I avoid licorice if I have high blood pressure?
How many DGL tablets am I supposed to chew each day?
Why do some people say DGL capsules did not work for them?
Do DGL supplements need to be taken at a specific time?
Final Thoughts: The Verdict
For most people working through this list of the dgl supplement, the winner is the Integrative Therapeutics Rhizinate Fructose Free because it pairs a chewable format with a stated glycyrrhizin level under 1% and skips sugar entirely. If you would rather swallow a capsule and want organic certification, grab the Zazzee USDA Organic DGL Licorice 20:1. And for the biggest capsule count in a single bottle, the Carlyle DGL is the one to reach for.
One last thing worth doing before you buy: read the serving size on your own bottle once it arrives. A 200-capsule bottle looks like half a year of supply until the panel says two capsules per serving — and that one line is the difference between a bargain and a reorder.
How We Picked
We do not accept paid placement. Every pick is matched to a real buyer and a real use-case; we do not hands-on test units.
Sources & Methodology
Specifications: manufacturer listings and product documentation. Review insights: verified customer reviews, as of September 2026. Pricing: not shown on this page (it changes often); check the current price via the retailer link.
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