How to Disinfect Used Shoes | Safe Steps That Work

For the full breakdown, see our best Disinfectant Spray for Shoes guide.

Secondhand shoes can carry bacteria, fungi, and viruses that cause everything from athlete’s foot to more serious infections. The good news is that the process of disinfecting used shoes is straightforward — you don’t need a professional service or special equipment.

Start With a Thorough Cleaning

Disinfectant doesn’t work well on dirt. Organic material and debris shield microbes from the product, which is why cleaning comes first. The CDC’s guidance on cleaning and disinfecting is clear that surfaces need to be cleaned of visible soil before a disinfectant can do its job.

Do this step outside or in an entryway, not on carpet:

• Remove the laces and set them aside — you’ll clean them separately.
• Brush or wipe off loose dirt, mud, and debris from the entire shoe.
• Scrub the soles and uppers with mild soap and warm water.
• Wipe away soap residue with a clean damp cloth.

For the laces, soak them in warm soapy water while you disinfect the shoes, then rinse and let them dry.

How Long Should Disinfectant Stay On Shoes?

The single biggest mistake people make is wiping on a disinfectant and immediately rinsing it off. Disinfectants need time to work — most require the surface to stay wet for roughly 3–5 minutes, though you should always follow the contact time printed on your specific product’s label. If the surface dries before that time is up, reapply and restart the clock.

Wearing shoes while they’re still damp isn’t just uncomfortable — it can leave residual chemicals against your skin and keep microbes alive longer.

Disinfecting Methods That Work on Sneaker Materials

Not all shoes can handle the same treatment. Bleach, hydrogen peroxide, and rubbing alcohol can discolor or damage certain fabrics and finishes, so test any method on a small, hidden area first.

Drying and Final Checks

Stuff them with paper towels to absorb moisture and help them hold their shape, and keep them in a well-ventilated area away from direct heat, which can warp glue and materials.

Once dry, check for any lingering odor or visible staining. If you’re dealing with heavily used shoes that show signs of mold or deep contamination, consider whether professional cleaning is the safer route.

Dirty or secondhand shoes may carry infectious diseases, so when a thorough cleaning and disinfecting routine isn’t enough, don’t gamble with your health.